The Coronavirus (CoV) is a large family of viruses known to cause illnesses ranging from the common cold to acute respiratory tract infection. The severity of the infection may be visible as pneumonia, acute respiratory syndrome, and even death.9 Coronaviruses being positive-sense, enveloped, single-stranded RNA viruses, are capable of affecting a wide range of host species. It contains four structural proteins-Spike (S), membrane (M), envelop (E) and nucleocapsid (N).10 They have an average size of of ~30 kb and are divided into four genera; α, β, γ, and δ. Mammals are affected by the α and β coronaviruses. Human coronaviruses 229E and NL63 responsible for common cold and croup and belong to α coronavirus family. Angiotensin converting enzyme 2 (ACE2) was identified as a functional receptor for SARS-CoV. ACE2 expression was high in lung, heart, ileum, kidney and bladder.11 target needs further investigation. Following the binding of SARS-CoV- 2 to the host protein, the spike protein undergoes protease cleavage.